Long-term follow-up of thalamic deep brain stimulation for essential and parkinsonian tremor.
Identifieur interne : 002D74 ( Main/Exploration ); précédent : 002D73; suivant : 002D75Long-term follow-up of thalamic deep brain stimulation for essential and parkinsonian tremor.
Auteurs : Rajeev Kumar [Canada] ; Andres M. Lozano ; Elspeth Sime ; Anthony E. LangSource :
- Neurology [ 1526-632X ] ; 2003.
English descriptors
- KwdEn :
- MESH :
Abstract
Thirteen consecutive patients with thalamic deep brain stimulation (DBS) were examined serially for 3 to 5 years. Initially, all demonstrated at least 50% improvement in contralateral tremor. At last follow-up, three of eight patients with Parkinson disease no longer used DBS because tremor had markedly improved, and for two, motor fluctuations and levodopa-induced dyskinesias became the major disability, with tremor less troublesome. Two of five patients with essential tremor had contralateral tremor improvement after ongoing stimulation for 2 years; two developed marked tolerance to DBS.
PubMed: 14663050
Affiliations:
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Le document en format XML
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<term>Follow-Up Studies</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Parkinson Disease (surgery)</term>
<term>Thalamus (surgery)</term>
<term>Treatment Outcome</term>
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<front><div type="abstract" xml:lang="en">Thirteen consecutive patients with thalamic deep brain stimulation (DBS) were examined serially for 3 to 5 years. Initially, all demonstrated at least 50% improvement in contralateral tremor. At last follow-up, three of eight patients with Parkinson disease no longer used DBS because tremor had markedly improved, and for two, motor fluctuations and levodopa-induced dyskinesias became the major disability, with tremor less troublesome. Two of five patients with essential tremor had contralateral tremor improvement after ongoing stimulation for 2 years; two developed marked tolerance to DBS.</div>
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<country name="Canada"><region name="Ontario"><name sortKey="Kumar, Rajeev" sort="Kumar, Rajeev" uniqKey="Kumar R" first="Rajeev" last="Kumar">Rajeev Kumar</name>
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